Lidocaine CRI
Posted: Monday, January 16th, 2023 | Updated: Monday, January 16th, 2023
Posted: Monday, January 16th, 2023 | Updated: Monday, January 16th, 2023
Doctor's Order:
Start a Lidocaine CRI at 50 mcg/kg/min. Draw up 12 hours worth
Patient Weight:
15 kg
Lidocaine Concentration:
20 mg/ml or 2%
Convert the Lidocaine from mg to mcg:
(20 mg/ml) x (1000 mcg/mg) = 20,000 mcg/ml concentration of Lidocaine
Complete the Math:
(50 mcg/kg/min) x (15 kg) = 750 mcg/min Lidocaine
(750 mcg/min) x (60 min/hr) = 45,000 mcg/hr Lidocaine
(45,000 mcg/hr) / (20,000 mcg/ml) = 2.25 ml/hr Lidocaine
(2.25 ml/hr) x (12 hr) = 27 ml Lidocaine
The Result:
You will need 27 ml of Lidocaine to run the CRI at 50 mcg/kg/min or 2.25 ml/hr for 12 hours
*Note Per Plumb's as of 01/16/23: "Lidocaine may not be compatible with dopamine, epinephrine, isoproterenol, or norepinephrine as these require low pH for stability. Lidocaine is reportedly physically incompatible when mixed with ampicillin, cefazolin, diazepam, pantoprazole, pentobarbital, or sulfa-/trimethoprim."
Start a Lidocaine CRI at 50 mcg/kg/min. Draw up 12 hours worth
Patient Weight:
15 kg
Lidocaine Concentration:
20 mg/ml or 2%
Convert the Lidocaine from mg to mcg:
(20 mg/ml) x (1000 mcg/mg) = 20,000 mcg/ml concentration of Lidocaine
Complete the Math:
(50 mcg/kg/min) x (15 kg) = 750 mcg/min Lidocaine
(750 mcg/min) x (60 min/hr) = 45,000 mcg/hr Lidocaine
(45,000 mcg/hr) / (20,000 mcg/ml) = 2.25 ml/hr Lidocaine
(2.25 ml/hr) x (12 hr) = 27 ml Lidocaine
The Result:
You will need 27 ml of Lidocaine to run the CRI at 50 mcg/kg/min or 2.25 ml/hr for 12 hours
*Note Per Plumb's as of 01/16/23: "Lidocaine may not be compatible with dopamine, epinephrine, isoproterenol, or norepinephrine as these require low pH for stability. Lidocaine is reportedly physically incompatible when mixed with ampicillin, cefazolin, diazepam, pantoprazole, pentobarbital, or sulfa-/trimethoprim."
Sources:
Plumb's Veterinary Drugs App accessed from Instinct on 01/16/23.
Plumb's Veterinary Drugs App accessed from Instinct on 01/16/23.