Ketamine CRI
Posted: Tuesday, October 12th, 2021 | Updated: Tuesday October 12th, 2021
Posted: Tuesday, October 12th, 2021 | Updated: Tuesday October 12th, 2021
Doctor's Order:
Start a Ketamine CRI at 0.2 mg/kg/hr.
Patient Weight:
13 kg
Standard Dilution Protocol (Varies By Hospital):
Dilute Ketamine with 0.9% NaCl where 0.1 mg/kg/hr = 1 ml/hr and create a 10 hour CRI at that rate
Ketamine Concentration:
100 mg/ml
Complete the Math:
(0.1 mg/kg/hr) x (13 kg) = 1.3 mg/hr Ketamine
(1.3 mg/hr) / (100 mg/ml) = 0.013 ml/hr of Ketamine
(0.013 ml/hr) x (10 hr) = 0.13 ml Ketamine
(10 ml Total Fluid Volume) - (0.13 ml Ketamine) = 9.87 ml 0.9% NaCl
The Result:
You will need 0.13 ml of Ketamine to mix with 9.87 ml of 0.9% NaCl. This will result in 0.1 mg/kg/hr = 1 ml/hr. To run the Ketamine CRI at 0.2 mg/kg/hr, increase the fluid rate of your CRI to 2 ml/hr
*Note Per Plumb's as of 10/12/21: "Ketamine appears to be Y-site incompatible with ampicillin sodium, dexamethasone sodium phosphate, furosemide, heparin, insulin (regular), and sodium bicarbonate."
Start a Ketamine CRI at 0.2 mg/kg/hr.
Patient Weight:
13 kg
Standard Dilution Protocol (Varies By Hospital):
Dilute Ketamine with 0.9% NaCl where 0.1 mg/kg/hr = 1 ml/hr and create a 10 hour CRI at that rate
Ketamine Concentration:
100 mg/ml
Complete the Math:
(0.1 mg/kg/hr) x (13 kg) = 1.3 mg/hr Ketamine
(1.3 mg/hr) / (100 mg/ml) = 0.013 ml/hr of Ketamine
(0.013 ml/hr) x (10 hr) = 0.13 ml Ketamine
(10 ml Total Fluid Volume) - (0.13 ml Ketamine) = 9.87 ml 0.9% NaCl
The Result:
You will need 0.13 ml of Ketamine to mix with 9.87 ml of 0.9% NaCl. This will result in 0.1 mg/kg/hr = 1 ml/hr. To run the Ketamine CRI at 0.2 mg/kg/hr, increase the fluid rate of your CRI to 2 ml/hr
*Note Per Plumb's as of 10/12/21: "Ketamine appears to be Y-site incompatible with ampicillin sodium, dexamethasone sodium phosphate, furosemide, heparin, insulin (regular), and sodium bicarbonate."
Sources:
Plumb's. Vers. 2021.9.3. Educational Concepts, LLC. Google Play, https://play.google.com/store/apps/details?id=com.plumbs.app.
Plumb's. Vers. 2021.9.3. Educational Concepts, LLC. Google Play, https://play.google.com/store/apps/details?id=com.plumbs.app.